(A) scRNA-seq with ST can reveal spatial zonation profiles of gene expression in the normal liver and a detailed cell landscape of the human liver, showing that 50% of liver genes have partitioning ...

The liver's ability to communicate with other organs is crucial for maintaining homeostasis, particularly through signaling pathways. During liver regeneration, communication with organs such as the ...

Intestinal-specific Hdac3 deletion increases susceptibility to colitis and small intestinal tumor development in mice fed a high-fat diet.

Chronic liver damage can lead to hepatitis, which causes fibrosis of the liver. This buildup of collagen and other fibrous tissue accelerates when hepatic stellate cells become activated during ...

What a mother eats during pregnancy may quietly shape her child’s liver health years down the road—but new research suggests ...

Metabolic dysfunction-associated steatotic liver disease (MASLD), formerly known as nonalcoholic fatty liver disease, is the most common chronic liver disease, affecting almost 40% of adults worldwide ...

A long-term study found that while a ketogenic diet prevented weight gain, it also triggered major metabolic problems. Mice developed fatty liver disease, abnormal blood fats, and an impaired ability ...

Metabolic dysfunction-associated steatotic liver disease is the most common liver disease in the world, affecting about one-third of the adult population. This disorder is characterized by the ...

Children whose mothers eat a diet high in fat and sugar during pregnancy and breastfeeding face a greater chance of developing fatty liver disease ...