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The PPT/TSTA expression cassette mediates high and prostate-specific transcriptional activity. The PPT/TSTA-Luc system is schematically outlined in Figure 1a.The PPT regulatory sequence drives the ...
Rapamycin-induced AR transcriptional activity on hPSA-luc was inhibited by Akt siRNA in C4-2 cells, whereas basal levels were minimally affected . Further, transfection ...