Lysosomes are membrane-bound organelles whose acidic lumen (pH 4.5–5.0) is required for degradation. This luminal acidity is ...

Researchers at the Icahn School of Medicine at Mount Sinai have discovered how to reverse aging in blood-forming stem cells in mice by correcting defects in the stem cell's lysosomes. The breakthrough ...

Transmission electron microscopic image of an isolate from the first U.S. case of COVID-19, formerly known as 2019-nCoV. The spherical viral particles, colorized blue, contain cross-section through ...

CHICAGO (CBS) -- Lysosomes – membrane-bound structures within each cell of humans and all animals – are sometimes known as the cells' "garbage disposals" or "cellular janitors." The structures are ...

In a rare disease called mucolipidosis type II, people's hearts and abdomens swell, and their bones grow malformed. A lysosomal storage disorder, mucolipidosis type II causes edema of the internal ...

Functioning brain cells need a functioning system for picking up the trash and sorting the recycling. But when the cellular ...

Scientists at St. Jude Children’s Research Hospital discovered that metabolism controls regulatory T cells, the “brakes” of the immune system (MEMPHIS, Tenn. – October 24, 2025) Metabolism guides the ...

Knowing which lysosomal proteins are enriched in which brain cell types will help better understand contribution to neurological disorders.