Membrane proteins are vital for cellular signaling, transport, and communication, making them attractive drug targets despite their challenging properties. Advances in mass spectrometry have enabled ...

Researchers have developed a computational method to explicitly consider the impact of water while designing membrane receptors with enhanced stability and signaling, paving the way for novel drug ...

This table lists the main function, subclasses, main mediator cells and probable pathways and states the effect on regeneration, as promoting (+) or inhibiting (-). BDNF: Brain-derived neurotrophic ...

Identifying players involved in pain detection or cancer initiation, progression, and metastasis Determining intrinsic protein function in reconstituted systems Revealing structural mechanisms with a ...

The behaviour of a receptor protein can be influenced by the presence of certain lipids in the membrane it is embedded in.

Adaptor protein (AP) complexes play central roles in intracellular vesicular trafficking by coupling cargo selection to ...

Researchers at Washington University in St. Louis have a unique resource in the form of the Center for Biomolecular ...