The transport cycle of TRAP transporters is depicted schematically in the middle of the figure. To trap the transporter in specific states, the stator and elevator domains were cross-linked by ...
In a study published in Nature on January 28, a research team led by Eric H. Xu (Xu Huaqiang) from the Shanghai Institute of ...
The study of peptide transport mechanisms and membrane proteins has gained considerable momentum as researchers unravel the molecular intricacies underlying nutrient uptake, intracellular signalling ...
Using cryo-EM structure determination, molecular dynamics simulations, and electrophysiological analyses, researchers from the Shanghai Institute of Materia Medica of the Chinese Academy of Sciences ...
Pi plays crucial metabolic and structural roles in living organisms. It is essential for bioenergetics (ATP, GTP), metabolic regulation through glycolysis and oxidative phosphorylation, intercellular ...
Adaptor protein (AP) complexes play central roles in intracellular vesicular trafficking by coupling cargo selection to ...
In a study published in Nature on January 28, a research team led by Eric H. Xu (XU Huaqiang) from the Shanghai Institute of Materia Medica of the ...
A team of the University of Barcelona (UB) and the August Pi i Sunyer Biomedical Research Institute (IDIBAPS) identified a mechanism involved in the movement of cholesterol inside the cells. The study ...