Mitochondrial DNA has long been treated as a workhorse record of cellular history, but new research suggests it also hides a subtle and previously overlooked form of damage. By uncovering this cryptic ...

"Hearst Magazines and Yahoo may earn commission or revenue on some items through these links." Here’s what you’ll learn when you read this story: Many degenerative diseases are at least partially ...

When our body fights an infection, the immune system must quickly activate defenses and trigger a beneficial inflammatory ...

Tiny structures inside your cells keep your body alive by turning food into fuel. These structures, called mitochondria, power every heartbeat, thought, and movement. When they fail, organs that need ...

A previously unknown type of DNA damage in the mitochondria, the tiny power plants inside our cells, could shed light on how our bodies sense and respond to stress. The findings of the UC ...

In a step toward treating mitochondrial diseases, researchers in the Netherlands have successfully edited harmful mutations in mitochondrial DNA using a genetic tool known as a base editor. The ...

Autophagy activators such as kaempferol/emodin (via the PINK1/Parkin pathway) and spautin-1 (stabilizing PINK1 activity) clear damaged mitochondria, while gene therapy targets mtDNA mutations to ...

Muscle weakness from long-term alcoholism may stem from an inability of mitochondria, the powerhouses of cells, to self-repair, according to a study funded by the National Institutes of Health. In ...