The structural and functional characteristics of mitochondria shape their role as signaling organelles, with far-reaching ...

More than 150 human diseases — including Lou Gehrig’s, Parkinson’s and Alzheimer’s — are linked to mitochondrial failure, and one Nebraska scientist is working to decode why. A five-year, $2 million ...

They fall into the following main categories: mitochondria-targeted antioxidants, modulating mitochondrial dynamics, enhancing mitochondrial quality control, potentiating mitochondrial biogenesis, ...

Mitochondria are incredible organelles. They not only provide crucial power to our cells, but these little machines also have their own tiny little genomes, and can even make their own proteins. But ...

How One Tiny Cellular Structure Holds the Key to Better Health & Longevity — and How You Can Harness It ...

A long-studied metabolic hormone, FGF21, also acts as a stress hormone—a discovery that helps explain how psychological stress causes metabolic dysregulation and drives physical disease, according to ...

The energy factories in our cells contain their own genes, and genetic mutations in them can cause deadly inherited diseases. These oblong-shaped organelles, or mitochondria, translate genes into ...

The AHA recommended whole exome or whole genome sequencing as first-line diagnostic tools for mitochondrial diseases.

Area of Focus: mitochondrial quality control, cellular metabolism, immune responses and the mechanisms underlying neurodegenerative diseases. Fourteen years ago, Xin Qi joined the Department of ...

As of 2019, about 4.9 million people globally were living with an inflammatory bowel disease (IBD) such as Crohn’s disease. Scientists are still unclear as to the exact cause of Crohn’s disease, which ...