Using technologies like electron microscopy (EM) it is possible to capture molecular mechanisms in great detail, but not when these mechanisms are currently moving. The field of cryomicroscopy ...
A University of Massachusetts Amherst kinesiologist has received a five-year, $2 million grant from the National Institutes of Health (NIH) to advance his research on how myosin molecules—molecular ...
A human heart might contract some three billion times over a lifetime, and each one of those contractions is driven by a protein called myosin. One of three classes of so-called motor proteins in our ...
MINNEAPOLIS -- The small-molecule drug candidate danicamtiv showed promise for activating myosin in gene-related dilated cardiomyopathy (DCM), based on a small phase IIa study. Suggesting boosted ...
JUPITER, Fla., June 9, 2025 /PRNewswire/ -- Myosin Therapeutics, Inc., a clinical-stage biotechnology company developing first-in-class therapies targeting molecular motors, today announced that the U ...
The novel cardiac myosin inhibitor aficamten improved peak oxygen uptake in symptomatic obstructive hypertrophic cardiomyopathy (HCM), the pivotal SEQUOIA-HCM trial showed. At 24 weeks, the mean ...