Chronic intermittent hypoxia forces the blood vessels in the lung to make more NADPH oxidase, Hart and his colleagues found. Mice that lack NADPH oxidase are immune to hypoxia’s effects.

Figure 2: Cellular and subcellular expression of NADPH oxidase isoforms in the blood vessel wall. Although NOX4 oxidase and NOX5 oxidase could emerge as validated drug targets from future research ...

Insufficient oxygen to an area like the heart or legs, called hypoxia, is a cue to our bodies to make more blood vessels ... then in turn activates NADPH oxidase, a family of enzymes that generate ...

Perivascular macrophages—those innate immune cells sitting oh-so-innocently on the small blood vessels in our brains—might ... source of free radicals in response to ApoE4, while the NADPH oxidase ...

The current study found a protective effect of the T allele of the missense rs4673 polymorphism of the cytochrome b-245 alpha chain (CYBA) gene, encoding the p22phox subunit of nicotinamide adenine ...

A recent Nutrients narrative review study examined the existing scientific evidence on the role played by garlic in effectively lowering blood pressure ... phosphate (NADPH) oxidase and trap ...

"Adipose tissue-derived WNT5A regulates vascular redox signaling in obesity via USP17/RAC1-mediated activation of NADPH oxidases." view more ...

Expression of NADPH oxidase component protein was detected by means of immunoblotting, and the affected genes were sequenced to identify causal mutations. Patients with chronic granulomatous ...

The researchers found that ROS levels were elevated in macrophages from the colitis and periodontitis groups, with increased expression of NADPH oxidase-related genes. This was particularly ...