Narcolepsy, with or without cataplexy, can have a substantial detrimental effect on well-being and quality of life. Because there is no cure for this condition, current treatments aim to improve ...

Pitolisant (Wakix) in children ages 6 years and up led to clinically meaningful improvements in narcolepsy symptoms in a phase III trial. Among 110 kids with narcolepsy with or without cataplexy, ...

Narcolepsy was linked to high blood pressure, hyperlipidemia, and diabetes on top of outright cardiovascular disease events in a retrospective cohort study. Notably, patients with narcolepsy started ...

Please provide your email address to receive an email when new articles are posted on . Most participants with narcolepsy with cataplexy who took the sodium oxybate therapy Xyrem at the beginning of a ...

Narcolepsy is a disorder caused by losing orexin neurons, marked by excessive daytime sleepiness and cataplexy, and sudden weakening of muscle control. Previously, we found two kinds of neurons ...

Please provide your email address to receive an email when new articles are posted on . Data suggest that pitolisant, a histamine 3-receptor antagonist/inverse agonist under development for narcolepsy ...

Cataplexy, or sudden muscle weakness that can resemble fainting, may be prompted by strong emotions. This symptom isn't serious and mostly occurs with narcolepsy type one — otherwise, it's very rare.

Researchers at the University of Helsinki have identified influenza virus peptides that resemble human protein fragments and can cause an immune response against the body's own cells due to ...

Narcolepsy is a neurological disorder that is characterized by excessive daytime sleepiness and cataplexy—a loss of muscle tone generally triggered by certain strong emotions with sudden onset. The ...

For years, Julie Flygare kept her condition private. She hadn’t liked people’s reactions on the occasions when she had opened up and shared her story. People thought it was a joke or not important. In ...