Modified nucleosides, regarded as indicators for the whole-body turnover of RNAs, are excreted in abnormal amounts in the urine of patients with malignancies. To test their usefulness as tumour ...

Secondly, modified nucleosides altered the ability of RNA to stimulate the production of cytokines, such as TNF-α and IL-12, and thus their capacity to activate dendritic cells (DCs).

If oxidized nucleosides are incorporated into DNA, they can wreak havoc on gene expression, causing mutations and DNA damage that can be toxic to cells.

Cite this: ACTG 5095: Triple Nucleosides Redux - Medscape - Jun 01, 2004. Tables. Authors and Disclosures. Authors and Disclosures. Dr. Sax is Editor-in-Chief of ACC. Comments ...

Chemical production of pyrimidine nucleosides by a number of primarily Chinese and Indian companies has allowed oligos, incorporating modified uridines and cytosines, to be generated cost ...

Deazaguanosine nucleosides, in particular, are of significant interest for their antibacterial, antifungal, antiviral, and anticancer activity.

Applications of Sustainable Chemistry in the Synthesis of Nucleosides, Nucleotides and Oligonucleotides Sustainable Chemistry in the Synthesis of Nucleosides, Nucleotides and Oligonucleotides. Virtual ...

Nucleosides and nucleotides remain one of the most fruitful drug classes, providing about 50% of antiviral drugs and 20% of cancer drugs used in the UK. Nucleoside and nucleotide chemistry constitute ...

Nucleosides are key structures for current drug development and have established roles as antivirals and anticancer agents. Their (poly)phosphorylated nucleotide counterparts are critical tools for ...

Suppression of Ehrlich ascites tumor cell proliferation via G1 arrest induced by dietary nucleic acid-derived nucleosides. PLOS ONE, 2024; 19 (7): e0305775 DOI: 10.1371/journal.pone.0305775; ...

Purine Nucleosides Interfere with c-di-AMP Levels and Act as Adjuvants To Re-Sensitize MRSA To β-Lactam Antibiotics. Article Publication Date. 12-Dec-2022. Disclaimer: ...