The lesions may arise spontaneously from thrombosis of arteries supplying the skin, with resultant infarction. In others, necrosis follows trauma or infection of the leg.

Dr. Mariko R. Yasuda: This 55-year-old man with chronic pancreatitis complicated by infected pancreatic necrosis presented with skin lesions at two discrete time points.

The differential diagnosis of prominent mucositis in conjunction with necrotic skin lesions should always include Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN), a severe ...

One of the most dreaded effects of the bite of the brown recluse spider (Loxosceles spp) is the appearance of a necrotic skin lesion, but a clinical study by Brazilian researchers recently ...

Warfarin-induced skin necrosis (WISN) occurs in only 0.01%-0.1% [1,4,5] of patients taking the drug; the incidence is higher in middle-aged women. This side effect typically appears during the ...

“You get these necrotic skin lesions, meaning these areas of dead tissue. I immediately thought I am already seeing those,” McElroy said. “It has probably been since last summer, ...

Coumadin-induced skin necrosis (CISN) is also known as warfarin-induced skin necrosis (WISN). It is a rare, unpredictable complication in response to oral anticoagulant therapy (warfarin), which ...