Further, although serum ferritin is recognized as a proinflammatory biomarker that is frequently elevated in a variety of autoimmune disorders, the role it plays in AAV still needs to be elucidated.

To be considered clinically relevant, a biomarker must have a high DA; [32] that is, it must have high sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) ...

Vitamin D deficiency has a causative role in the systemic inflammation that commonly accompanies it, with inflammation declining, reflected by reductions in elevated C-reactive protein (CRP), as ...