Poly(ADP‐ribose) polymerases (PARPs) are a family of enzymes that play a crucial role in maintaining genomic integrity by detecting DNA damage and facilitating its repair. By catalysing the covalent ...
Researchers have uncovered an early survival response in ovarian cancer cells that may limit the effectiveness of widely used ...
Scientists at Dartmouth Cancer Center have discovered that a common drug used to treat high blood pressure may also help fight cancer more effectively. The study, published in The Journal for ...
The article by George et al entitled “Phase II Trial of the PARP Inhibitor, Niraparib, in BAP1 and Other DNA Damage Response Pathway-Deficient Neoplasms” (JCO ...
In a new Dartmouth Cancer Center (DCC) study led by clinical researcher Tyler J. Curiel, MD, MPH, FACP, investigators found that the FDA-approved blood pressure drug telmisartan can significantly ...
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