Enzymatic cyclization of the linear polyketide chain to form a macrolactone is a key step in the biosynthesis of type I polyketide natural products. Structural biology and inhibitor design were used ...
A German-US coalition of researchers from Goethe University Frankfurt (Germany) and the University of Michigan (MI, USA) have added a new element to the production of an antibiotic, erythromycin, to ...
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