Protein phosphorylation is a key regulatory signaling event that can activate or deactivate protein function and regulate critical biochemical pathways. Phosphospecific antibodies represent research ...

A University of Dundee expert has been appointed to lead a new centre that will drive research to better understand the ...

A single protein may have multiple phosphorylation sites, which act as on/off switches for specific functions. The “switches'' are activated by a family of proteins known as kinases.

Recent research has observed that chemical modifications called phosphorylation of various proteins *1) in brain neurons dynamically regulates in controlling sleep and wakefulness. On the other ...

In addition, they examined "phosphorylation," or the biochemical addition of phosphate groups to protein structures, in five key proteins involved in memory formation.

SOKENDAI and Kyushu University have uncovered the molecular mechanism that drives the "ticking" of the circadian clock in ...

- Phosphorylation-inducing chimeric small molecules (PHICS) are a new class of bifunctional medicines that direct and repair aberrant and dysfunctional proteins ...

A recent research finding adds to evidence that brain inflammation is a major driver of neurodegenerative disorders such as ...

Scientists at the Broad Institute of MIT and Harvard have identified 4,208 previously unannotated open reading frames (ORFs) across 679 human-associated viral genomes using a high-throughput method ...

Interestingly, they observed that phosphorylation of a specific regulator called ARHGEF2 led to the activation of RhoA, which ...

More specifically, NMDAR activation triggers Ca 2+-dependent kinases, such as CaMKII, that phosphorylate other target proteins. Phosphorylation is a chemical process that modifies proteins, acting ...