A group of international researchers reports the availability of a new “map”’ of every gene, protein, and metabolic pathway required for a cell to efficiently secrete recombinant proteins. The team, ...

Oxidative stress induced by 6-OHDA stimulates autophagy flux, which enhances STX17-mediated autolysosome formation, leading to the degradation of autophagosomal contents. However, in response to ...

snoRNAs were thought simply to guide chemical modifications to rRNAs, but a new technique has revealed a suite of potential functions in protein secretion. A recent research effort from the University ...

Intracellular protein trafficking and secretion of proteins into the extracellular environment are sequential and tightly regulated processes in eukaryotic cells. Conventionally, proteins that are ...

Cell signaling pathways contain a wide range of secreted proteins and cytokines, and correctly quantifying these molecules is critical for basic research and therapeutic development. The role of the ...

Plant cell-based bioproduction systems are known for producing proteins with proper folding and post-translational modifications that have been used in a handful of approved therapeutics. Widespread ...

Every day, the liver packages fat and releases it into the bloodstream to fuel the body, supplying energy to the heart, muscles, and other organs during the active hours of the day. The liver does not ...

If diabetes suddenly develops or pre-existing diabetes rapidly worsens without specific reasons such as weight gain or ...