Protein trafficking is a fundamental cellular process that ensures efficient sorting, modification, and delivery of proteins to their correct subcellular destinations. At its core, this process ...

Adaptor protein (AP) complexes play central roles in intracellular vesicular trafficking by coupling cargo selection to ...

This article and associated images are based on a poster originally authored by Sabrina Heaton and presented at ELRIG Drug Discovery 2025 in affiliation with AstraZeneca. This poster is being hosted ...

Cognitive tasks, such as learning and memory, require rapid changes to proteins at synapses, such as protein synthesis, degradation, and trafficking. How protein post-translational modifications ...

Endosomal trafficking and protein sorting constitute fundamental processes that govern the intracellular localisation and recycling of membrane proteins in eukaryotic cells. Endosomes act as central ...

When it comes to neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS) and certain forms of dementia, ...