aProximate TM is an advanced in vitro model of kidney proximal tubule cells (PTCs) that closely mimics physiological conditions. Derived from fresh human kidney tissue, aProximate TM PTCs are cultured ...

This is a preview. Log in through your library . Abstract Our previous studies of microperfused single proximal tubule showed that flow-dependent Na⁺ and HCO₃⁻ reabsorption is due to a modulation of ...

The USC Stem Cell laboratory of Andy McMahon has identified a type of injured cell that might contribute to the transition from an acute kidney injury to chronic kidney disease, as described in a new ...

The calcium-sensing receptor (CSR) is a G-protein receptor that plays a critical role in calcium regulation. In the kidney, the CSR regulates calcium reabsorption in the thick ascending limb, where ...

Renal cell carcinoma, also called hypernephroma, is a cancer of the kidneys that forms in the proximal convoluted tubule. In the UK, it is the eighth most common cancer among adults, affecting 9,300 ...

The kidney's proximal tubule reabsorbs water, glucose, ions and other small molecules from the urine and thus maintains the body's supply of these essential constituents. The tubule can be easily ...