Rheumatoid arthritis (RA) is a chronic autoimmune disease in which the immune system mistakenly attacks the lining of the joints (the synovium), causing pain, swelling, and progressive damage.

Inflammatory markers were reduced in patients with persistent joint pain and other markers for incipient rheumatoid arthritis (RA), as was progression to formal RA diagnosis, after a 6-month course of ...

Two distinguishing features of long-standing RA are “swan neck” deformities and boutonniere deformities of the fingers (Figure 1). 3 Swan neck deformities develop with hyperextension of the PIP joint ...

Yi-Ping Li, Ph.D., Jay M. McDonald Endowed Professor in Bone Pathobiology, was recently awarded an R01 award from the National Institute of Arthiritis and Musculoskeletal and Skin Diseases titled, ...

Researchers at Kyoto University have discovered that an immune molecule found only in primates, called IGFL2, plays a key role in regulating inflammation in rheumatoid arthritis (RA). IGFL2 is ...

The IGFL2 gene encodes a cytokine found in primates, which are closely related to humans. In the joint tissue of people with rheumatoid arthritis, peripheral helper T (Tph) cells express IGFL2, which ...