Type I restriction enzymes cut DNA at random locations far from their recognition sequence, ... Watch an animation that shows how REs “cleave” their DNA targets.

Restriction enzymes are essential tools for recombinant DNA technology that have revolutionized modern biological research; however, they have limited sequence specificity and availability. The ...

Cloning DNA fragments using restriction enzymes is like flying from Seattle to New York via Phoenix. You arrive at your destination, but it takes longer than necessary to get there. Restriction sites, ...

The use of restriction enzymes as a way to cut DNA molecules was first demonstrated in a classic study by Johns Hopkins biochemist Daniel Nathans and his graduate student Kathleen Danna (Danna ...