Proceedings of the National Academy of Sciences of the United States of America, Vol. 104, No. 9 (Feb. 27, 2007), pp. 3444-3449 (6 pages) Titin is a giant protein that is in charge of the assembly and ...

In striated muscle, the giant protein titin spans the entire length of a half-sarcomere and extends from the backbone of the thick filament, reversibly attaches to the thin filaments, and anchors to ...

Using new high-resolution imaging techniques, MDC researchers and colleagues have tracked titin, the body’s largest protein, in real time throughout its entire lifecycle. The method and results could ...

Titin is a high-molecular weight protein (3.0-3.8 MDa) in the sarcomeres of vertebrate striated muscles. A plethora of titin isoforms is expressed from the copy of a single titin gene (on chromosome 2 ...

Using new high-resolution imaging techniques, MDC researchers and colleagues have tracked titin, the body's largest protein, in real time throughout its entire lifecycle. The method and results could ...

Although scientists have long speculated that a protein named titin measures thick filaments—the proteins that make muscles contract—no one has been able to provide evidence to support their theories.

Using new high-resolution imaging techniques, MDC researchers and colleagues have tracked titin, the body's largest protein, in real time throughout its entire lifecycle. The method and results could ...

Please provide your email address to receive an email when new articles are posted on . Seung Hoan Choi, PhD, of the program in medical and population genetics at The Broad Institute of MIT and ...

Imagine grabbing two snakes by the tail so that they can't wriggle off in opposite directions. Scientists at the Hamburg Outstation of the European Molecular Biology Laboratory (EMBL) and ...