Liquid chromatography-mass spectrometry (LC-MS) is fast becoming the gold standard for biopharmaceutical analysis. However, identifying which LC-MS-based technique is best suited to a particular ...

High-performance liquid chromatography-mass spectrometry (HPLC-MS) combines the separation power of LC with the detection specificity of MS. It has become an indispensable analytical tool in the ...

This is the final article in this series discussing HPLC oligonucleotide separations. This article will discuss LC/MS analysis of failure sequences, phosphorothioate modified siRNAs, CpG methylated ...

This article presents a comparative study to evaluate the sensitivity performance of the SCIEX 7500+ system for quantifying pesticides in orange juice. Food and beverage samples are well-known for ...

RNA-based therapeutics face challenges in bioanalysis, with experts recommending strategies to improve LC–MS performance and standardize ADME and DMPK practices. GLP-1 therapies require careful ...