Cancer Sponsored Somatic or Germline? Enhancing Tumor Profiling Accuracy Discover how matched tumor-normal sequencing reveals the true origin of variants May 2, 2025 Sponsored content brought to ...

Dr. Evan Yu presents the new evidence-based guideline on genetic testing for metastatic prostate cancer. He discusses who should receive germline and somatic testing with next-generation sequencing ...

Somatic mutations are, by definition, mutations that do not affect sex cells, so they are not inheritable. RNMSM prevalence was found to increase with age, as might be expected, with an average 50 ...

Somatic classifications were taken from reports from a single commercial TGP laboratory of tests ordered by providers at Huntsman Cancer Institute between March 2014 and June 2018. Somatic variant ...

Mutations have conventionally been categorized as either those arising in the germline or somatic mutations acquired during life. Deleterious germline mutations usually lead to conditions that ...

Drs Sandhya Srinivas and Heather Cheng discuss PARP inhibitors, clinical trials, and germline vs somatic testing for patients with prostate cancer, as well as the optimal time for this testing.

Educating Patients on Germline and Somatic Testing Drs Benjamin Levy and Lori J Wirth describe the differences between germline and somatic mutations, explain how these are detected and used to guide ...

Somatic human genome editing has made huge strides in the past five years, but the likely extremely high prices will be unsustainable. A global commitment to affordable, equitable access is urgently ...

A somatic cell is generally taken to mean any cell forming the body of an organism. Somatic cells, by definition, are not germline cells. In mammals, germline cells are the sperm and ova (also ...