The L1 stalk of the large ribosomal subunit undergoes large-scale movements coupled to the translocation of deacylated tRNA during protein synthesis. We use quantitative comparative structural ...

Transcription and translation are processes a cell uses to make all proteins the body needs to function from information stored in the sequence of bases in DNA. The four bases (C, A, T/U, and G in the ...

Overview of RNA repair – There is an emerging appreciation of the existence of “RNA repair” pathways that rely on RNA ligases to maintain or manipulate RNA structure in response to purposeful RNA ...

RNA, or ribonucleic acid, is a essential biological molecule that plays a crucial role in various cellular processes. It is a polymeric molecule composed of nucleotides, each containing a ribose sugar ...

All three RNAPs have catalytic cores consisting of 10 subunits. Five of these are core subunits which form crab claw shapes with DNA at their centres, channels for RNA products and NTP substrates as ...