Co-written with Jai Liester. Silent synapses represent one of neuroscience's most fascinating discoveries—connections between neurons that lie dormant until activated by specific triggers. These ...

Alzheimer’s may destroy memory by flipping a single molecular switch that tells neurons to prune their own connections. Researchers found that both amyloid beta and inflammation converge on the same ...

Scientists have discovered that the adolescent brain does more than prune old connections. During the teen years, it actively builds dense new clusters of synapses in specific parts of neurons. These ...

The DGIST Center for Synapse Diversity and Specificity has identified MDGA2 as a novel causative gene for developmental and ...

As we age, we begin to lose the connections that wire up our brains-and neuroscientists aren't sure why.

WASHINGTON — The brain’s nerve cells communicate by firing messages to each other through junctions called synapses, and problems with those connections are linked to disorders like Alzheimer’s and ...

Thinking, learning, feeling—all sensory perceptions are processed in the brain. Roughly 100 billion nerve cells are interconnected in the human brain. The lightning-fast communication between these ...

A study maps how toxic tau disrupts synapses over time, showing early postsynaptic damage that later spreads presynaptically.

Specific brain cells known as layer 5 pyramidal neurons play a vital role in how our brains process information. Research by the team of Prof. Joris de Wit (VIB-KU Leuven) and colleagues highlights ...