TGF-β signaling pathway mediates neuronal-intestinal mitochondrial stress response and lipid metabolism, finds study. Story by Chen Na • 3mo. Transforming growth factor-beta (TGF-β), ...

Researchers have identified a pathway that regulates B cell tolerance -- two proteins, GARP and TGF-beta, interact to temper B cell activity, thereby regulating autoimmunity.

Transforming growth factor-β (TGF-β) signaling plays a vital role in regulating cell growth, differentiation, and development in a wide array of biological systems.

TGF-β and HIPPO signaling pathways The TGF-β pathway is essential for regulating cell growth, differentiation, and immune responses. It functions as a tumor suppressor by inhibiting cell ...

A new study led by Baylor College of Medicine identifies an underlying mechanism of pathogenesis for osteogenesis imperfecta (OI) in human bone. The report, published in the Journal of Clinical ...

Two new mouse models of uterine cancer reveal that the TGF-beta signaling pathway in uterine cells protects against the disease by suppressing the overgrowth and oncogenesis of the endometrium ...

Transforming growth factor (TGF)-β signaling is an attractive therapeutic target as it is deregulated in many cancers. But challenges remain around developing inhibitors that can specifically block ...

"The TGF-beta signaling pathway regulates the development of many types of cancer, but it was not clear whether it also played a role in uterine cancer development," said corresponding author Dr ...

A new research paper was published in Genes & Cancer on February 5, 2023, entitled, "Mechanistically based blood proteomic markers in the TGF-β pathway stratify risk of hepatocellular cancer in ...

“The TGF-beta signaling pathway regulates the development of many types of cancer, but it was not clear whether it also played a role in uterine cancer development,” said corresponding author Dr.