CAR-T cells are specialized immune cells genetically modified to recognize and attack cancer cells. Researchers at Nagoya ...

A study in Chemistry A European Journal reveals that reduced MUC1 antigen density on gold nanoparticles still elicits potent ...

A mixture of proteins and other cellular components obtained by breaking open cells. In this study, tumor lysates were used to present a broad array of cancer antigens to the immune system. Overcoming ...

SNAs also enable scientists to tailor how these vaccine components are presented ... The team developed a cancer vaccine that doubled the number of cancer antigen-specific T cells and increased ...

Chimeric antigen receptor (CAR ... T cell therapy a more reliable and effective option for cancer treatment. CARs consist of three key components: an extracellular domain, an intracellular ...

[1] In their report, the authors develop weighted criteria to prioritize tumor vaccine antigens with the goal of identifying rational criteria to move individual antigens forward in development ...

Solid tumors are extremely heterogeneous and express a myriad of antigens ... have to understand critical components of T-cell recruitment and migration into the tumor,” Mehta noted.

Patients with myeloma whose tumor immune microenvironments had a ... "Two CAR T-cell therapies targeting the B-cell maturation antigen (BCMA) are now approved for the treatment of myeloma, but ...

Thus, identifying dietary components that prevent or inhibit ... AFDs to determine how the addition of these food antigens may affect tumor proliferation and immune responses.

Certain tumor markers may provide information about pancreatic cancer. Cancer antigen 19-9 (CA 19-9) is a type of tumor marker. Antigens are substances that cause the immune system to respond.