Eukaryotic translation initiation factors in trypanosomatids display a fascinating divergence from those in higher eukaryotes. Foundational research has revealed that these parasites possess multiple ...

Nuclear-encoded regulatory proteins control mitochondrial translation. A few, however, are encoded by the mitochondrial DNA (mtDNA) and are produced by the mitochondrial translation machinery.

Modern eukaryotic cells have proteins that enable chromosome segregation during cell division, new discoveries shed light on their origin in simpler prokaryotic organisms. Modern nucleated (eukaryotic ...

Prokaryotic cells, which include all bacteria and archaea, are ancient, and relatively simple compared to eukaryotic cells, which are found in fungi, plants, and animals. Scientists have long sought ...

CRISPR/Cas was first discovered in prokaryotes (bacteria and other single-cell organisms that lack nuclei) and scientists including Zhang's lab have long wondered whether similar systems exist in ...

A lot happened in the hundreds of millions years separating the first and last eukaryotic common ancestors, but when and how most features arose remains a mystery. Eukaryogenesis is broadly defined as ...

Proteins are essential biological molecules that perform a vast array of functions crucial for life, from catalyzing biochemical reactions and transporting molecules to providing structural support ...

All modern organisms fall into two classes, eukaryotes and prokaryotes. Eukaryotes (from the Greek meaning “true kernel”) have a cell nucleus that harbours most of the cell’s genetic information and ...