A Scripps team has adapted advanced imaging and computation to measure cell membrane thickness inside intact animal and yeast cells, uncovering organelle-specific differences and local patterns ...

Cellular membrane proteins play many important roles throughout the body, including transporting substances in and out of the cell, transmitting signals, speeding up reactions and helping neighboring ...

Scientists have uncovered new details about how cells manage the distribution of lipids in their cell membrane. These lipids, known as phospholipids, are arranged in a bilayer of membranes, regulating ...

Membrane proteins are vital for cellular signaling, transport, and communication, making them attractive drug targets despite their challenging properties. Advances in mass spectrometry have enabled ...

Researchers have created a deep learning pipeline for designing soluble analogues of key protein structures used in pharmaceutical development, sidestepping the prohibitive cost of extracting these ...

Cancer cells have softer membranes than healthy cells. New nanoparticles exploit this physical difference to fuse selectively with tumors and deliver mRNA therapy with minimal off-target effects.

Knowing which lysosomal proteins are enriched in which brain cell types will help better understand contribution to neurological disorders.

Adaptor protein (AP) complexes play central roles in intracellular vesicular trafficking by coupling cargo selection to ...