T24 and UMUC3 cell lines were treated with 1 mM and 5 mM valproate and 1 μM and 5 μM SAHA. Both cell lines showed a reduction in mitotic figures and proliferation under phase contrast (Figure 1). The ...

A recent study has unveiled the critical roles of two transcription factors, MAFB and CEBPA, in the development of hypospadias, a common congenital malformation affecting male urethral development.

5-Hydroxymethylated Biomarkers in Cell-Free DNA Predict Occult Colorectal Cancer up to 36 Months Before Diagnosis in the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial Pharmacodynamic ...

How bladder cancer originates and progresses has been illuminated as never before in a study led by researchers at Weill Cornell Medicine and the New York Genome Center. The researchers found that ...

JCO Precision Oncology Conversations features discussions with leading authors of JCO Precision Oncology articles, hosted by Dr. Abdul Rafeh Naqash. Join our experts in engaging conversations as they ...

Jelmyto shows long-term effectiveness in treating low-grade, upper tract urothelial carcinoma, with a high complete response rate in the OLYMPUS trial. The median duration of response for patients ...

Laparoscopic and open nephroureterectomy for upper urinary tract urothelial-cell carcinoma (UUT-UCC), which are uncommon but aggressive malignancies, are associated with comparable long-term outcomes, ...

UMUC-3 (ATCC CRL-1749) and T-24 (ATCC HTB-4) bladder cancer cell lines were purchased from the American Type Culture Collection (ATCC). They were grown and subcultured in Dulbecco's Minimal Essential ...