Impact of intratumor heterogeneity (ITH) on survival outcomes in patients with non-small cell lung cancer (NSCLC) with high tumor mutational burden (TMB-H).

“In the present study we describe the development of an inhibitory nanobody directed against an extracellular epitope present in the native V-ATPase c subunit.” “In the present study we describe the ...

In efforts to design microtubule polymerization inhibitors with the ability to induce immunogenic cell death (ICD), investigators from China Pharmaceutical University have discovered novel ...

A new research paper was published in Oncotarget's Volume 15 on August 14, 2024, entitled, "A nanobody against the V-ATPase c subunit inhibits metastasis of 4T1-12B breast tumor cells to lung in mice.

The rap sheet for β-CTF is growing longer. The C-terminal fragment, produced when β-secretase cleaves APP, binds to—and blocks assembly of—vacuolar ATPase, a proton pump that fuels acidification of ...

V-161, a novel compound targeting the Na+ -V-ATPase enzyme in vancomycin-resistant Enterococcus faecium (VRE), significantly ...

In efforts to design microtubule polymerization inhibitors with the ability to induce immunogenic cell death (ICD), investigators from China Pharmaceutical University have discovered novel ...