VHL is one of those diseases that you learn about in medical school but rarely see in practice, if ever. The NIH specializes in these “zebras.” ...

Von Hippel-Lindau (VHL) syndrome is a rare, inherited disease that causes the growth of cysts and tumors in various parts of the body. Learn more about VHL syndrome.

And this is important for VHL, but it’s also important for other cancer syndromes, too. (They can learn) what they can expect throughout their life dealing with this (condition) and it just is a way ...

Constitutive activation of the HIF transcription factor is responsible for the hypervascularization that occurs in VHL-disease–associated renal cell carcinoma. 1,7,8 Accordingly, VEGF-targeted ...

The identification in 1993 of inherited mutations in the von Hippel–Lindau (VHL) gene in families with VHL disease was a seminal finding. This and subsequent discoveries have given the VHLtumour ...

Inactivation of the von Hippel–Lindau (VHL) tumour-suppressor gene is linked to the development of several different tumour types in humans, including tumours of the kidney, retina, central ...

Hemangioblastomas often grow repeatedly in people with VHL. They are the cause of death for 82% of that group. Symptoms of a Hemangioblastoma. Large tumors put pressure on your brain and spine.

Feb. 10, 2011 — -- In a multi-episode arc on "Grey's Anatomy," actor Scott Foley plays a von Hippel-Lindau (VHL) patient, diagnosed with a dangerous adrenal tumor. Doctors at the ABC show's ...

Understanding the VHL Tumor Suppressor Complex. During the 1990s, several labs in the United States and United Kingdom investigated the von Hippel-Lindau tumor suppressor (pVHL). Jennifer Fisher ...

Among patients with other VHL-associated non-RCC tumors, results showed an ORR of 63% (95% CI, 41-81) in 24 patients with measurable CNS hemangioblastomas and an ORR of 83% (95% CI, 52-98) in 12 ...

According to rarediease.org, only 10,000 cases have been documented in the United states and according to UAB, the chance of a VHL holder being de novo is 20%.(De novo meaning the VHL holder did ...