(B) Hypothetical pedigree and molecular analysis showing germ-line mosaicism in tuberous sclerosis ... DNA analysis reveals that the father's germ cells, but not other tissues, harbour the ...

Mutations can be grouped into two main categories based on where they occur: somatic mutations and germ-line mutations. Somatic mutations take place in non-reproductive cells. Many kinds of ...

Two weeks after a human egg is fertilized, primordial germ cells (PGCs), which develop into sperm and eggs, are formed. In six to 10 weeks after fertilization, PGCs differentiate into pro ...

The nucleus of a germline stem cell undergoes two divisions, firstly separating homologous chromosomes and secondly separating chromatids. Haploid gametes contain 23 single chromosomes.