A genomic study of human and selected nonhuman primate centromeres has revealed their unimaginable diversity and speed of evolutionary change. Although centromeres are vital to proper cell replication ...

The centromere of chromosomes plays a crucial role in cell division. Using the model plant Arabidopsis thaliana, an international team of researchers has investigated how two crucial proteins -- KNL2 ...

Super-resolution microscopy image of a mitotic chromosome (white) with the centromeres of each sister chromatid depicted in orange. Each centromere consists of two distinct chromatin subdomains ...

Researchers from the Kops group in collaboration with researchers from the University of Edinburgh, made a surprising new discovery in the structure of the centromere, a structure that is involved in ...

"For decades, the centromere has been a genomic blind spot. Now, with complete assemblies and detailed repeat maps, we can begin to ask new questions about how centromeres originate, diversify, and ...

Six years ago, when Glennis Logsdon was a graduate student, everyone assumed that centromeres had conserved sequences and structures given their essential role in divvying up genetic material. “We had ...

Advancements in genome sequencing have challenged the long-standing belief that the position of the centromere in the chromosome is fixed. Researchers from Okayama University, Japan, have analyzed ...

Despite the immense amount of genetic material present in each cell, around three billion base pairs in humans, this material needs to be accurately divided in two and allocated in equal quantities.

Due to their repetitive and complex DNA sequences, centromeres have been viewed as the "black boxes" of the genome for decades. Often overlooked in sequencing projects but playing a critical role in ...

Just one enzyme manages the refilling of the cellular soda machine that replicates our genes. PLK-1 initiates a process in two protein groups, leading to creation of new CENP-A proteins. These CENP-A ...