Enantiomers, or molecule pairs that are mirror images of each other, make up more than half of FDA-approved drugs in use ...

An essential feature of the compound is its chirality at the atom of zinc in the center of the molecule. A chiral molecule comes in two versions, called enantiomers. The enantiomers are made of ...

An essential feature of the compound is its chirality at the atom of zinc in the center of the molecule. A chiral molecule comes in two versions, called enantiomers. The enantiomers are made of ...

Direct asymmetric syntheses of chiral phosphates and phosphoramidates ... candidate with 99:1 stereoselectivity at the phosphorus center and 92% yield (shown)—well suited to drug manufacturing.

“Most people don’t think about an amine being chiral because it rapidly interconverts ... pyramidal shape can tunnel through the N center, flipping the molecule inside out like an umbrella ...

The new method enables what had been impossible except in narrow cases: creating a center of chiral asymmetry at a hard-to-reach position called the "gamma" position on a cyclic carboxylic acid.

It creates a structure that chemists call an α-chiral center, thereby enabling the synthesis of a great variety of potentially valuable chiral drugs and other products. At the same time ...

have been shown to switch chirality upon exposure to light, heat, redox reactions, changes in pH or binding with other molecules, for example by inserting organic molecules at the metal center of ...

Chirality refers to objects that cannot be ... The MPSD is a member of the Center for Free-Electron Laser Science (CFEL), a joint enterprise with DESY and the University of Hamburg.