The cost of the New England Patriots' Week 18 win was the loss of a No. 1 pick. Joe Milton III went 22-of-29 for 241 yards with two total touchdowns on

Joe Milton III passed for a touchdown and ran for another in his NFL debut, and the New England Patriots cost themselves the No. 1 overall pick in the NFL draft with a 23-16 win over the AFC East champion Buffalo Bills.

That means Milton could be preparing to make his first appearance in an NFL regular season game. On the Patriots’ list of inactives, there were a total of six players ruled out for the game, including cornerback Christian Gonzalez and tight end Hunter Henry.

Joe Milton III threw for one touchdown and rushed for another in his NFL debut to guide the New England Patriots to a 23-16 victory over the Buffalo Bills on Sunday afternoon in Foxborough, Mass.

AFC East rivals on opposite ends of the standings face off in NFL Week 18 as the New England Patriots (3-13) host the Buffalo Bills (13-3) on CBS and Paramount+. The Bills have locked in the No. 2 seed in the AFC playoff picture and enter the regular-season finale on a three-game winning streak.

The Buffalo Bills (13-3) head to Gillette Stadium on Sunday to face the New England Patriots (3-13) in a Week 18 season finale AFC East matchup.

The New England Patriots ended a six-game losing streak and tied last year’s regular season record in Sunday’s 23-16 win over the Buffalo Bills. Fans would have rather seen the Patriots tank the season finale to guarantee the No.