Purpose: The clinical benefits, adverse effects, pharmacokinetics, and recommendations for the appropriate use of the aldosterone antagonists spironolactone and eplerenone in patients with heart ...

They tested this new method on 128 patients with high blood pressure caused by high levels of aldosterone. In about ...

Aldosterone antagonists (spironolactone, eplerenone) also known as “potassium sparing diuretics” block the action of aldosterone inhibiting the reuptake of sodium and water. Normally, when ...

The aldosterone-renin ratio (ARR) has gained popularity as a screening test for primary hyperaldosteronism, a probably underdiagnosed cause of hypertension. However, studies have yielded varying ...

Perspectives from Keith Churchwell, MD, FAHA Keith C. Ferdinand, MD CHICAGO — The investigational aldosterone synthase inhibitor lorundrostat effectively lowered 24-hour BP for adults with well ...

A recent study suggests that ultrasound-guided radiofrequency ablation (EUS-RFA) may be an effective and safe treatment ...

INVESTIGATIONS by F. C. Bartter et al. and by G. Farrell and his collaborators 1 on the regulation mechanism of aldosterone secretion have indicated a close relationship between blood volume and ...

“Currently available therapies to treat hypertension do not decrease aldosterone production in the body, and we know aldosterone dysregulation is a driving factor in the blood pressure elevation ...