The cysteine protease family called caspases is composed ... which leads to processing and activation of caspase 1. Active caspase 1 causes pyroptosis and is responsible for proteolytic maturation ...

This mouse model of EPM1 provides evidence that cystatin B, a non-caspase cysteine protease inhibitor, has a role in preventing cerebellar apoptosis. We micro-injected cells from three of six ...