Please use one of the following formats to cite this article in your essay, paper or report: APA. Sidharthan, Chinta. (2025, January 16). Androgen clock reveals how hormones shape aging and health.

Phase I Evaluation of Prolonged-Infusion Gemcitabine With Irinotecan for Relapsed or Refractory Leukemia or Lymphoma ABSTRACT: Androgen receptor (AR) is a member of the steroid hormone receptor family ...

The androgen receptor in prostate cancer cells can activate different sets of genes depending on whether it binds with an androgen hormone or an antiandrogen drug, according to a new study. The ...

In contrast to other steroid receptors, such as ERα, the activation function of androgen receptor (AR) is largely dependent on its ligand-independent AF-1 located in its N-terminal domain (NTD).

Background: AR ligand binding domain (LBD) activating somatic point mutation is a known mechanism of resistance to androgen-receptor signaling inhibitor (ARSI) treatment in mCRPC, leading to a ...

Evaluation of AR, AR-V7, and p160 family as biomarkers for prostate cancer: insights into the clinical significance and disease progression. Journal of Cancer Research and Clinical Oncology . doi ...

Prostate cancer, especially in advanced stages such as castration-resistant prostate cancer, is challenging to treat. Traditional therapies targeting androgen receptor (AR) signaling have limited ...

Arvinas Inc. – Arvinas to receive a $150 million upfront payment for the license of ARV-766 and the sale of Arvinas’ preclinical AR-V7 program, with the potential under the License Agreement ...

Using a staining cutoff of 40% AR staining among those with measurable breast cancer, ... a novel oral selective androgen receptor agonist, according to research presented at ASCO 2021.

Castration resistance is not unexpected, it is the inevitable outcome of chronic, prolonged exposure to androgen receptor (AR) blockade. The length of this period usually varies.