This step is a key point of regulation of gene expression in eukaryotes. Eukaryotic mRNAs ... their site of action in order to be biologically active. Also, by controlling the stability of ...

Mesophilic prokaryotic Argonautes (pAgos) have the potential to be developed into genome editing tools. Here, the authors report a mesophilic archaeal Ago that is catalytically active and utilizes ...

In prokaryotes, transcription initiation is the main point of control of gene expression. It is chiefly controlled by 2 DNA sequence elements of size 35 bases and 10 bases, respectively.

As CRISPRi is of much convenience and high efficiency, it has been widely applied for efficient gene regulation [7,8,9,10,11,12,13,14,15] and epigenetic studies [16,17,18,19,] in both prokaryotes ...

Many studies have correlated transcriptional activity or repression of a gene ... eukaryotes. Mapping pore association genome-wide will help determine whether NPC association is common to active ...

This mutation is directly linked to transcriptional activity: the more a promoter is active, the more frequently mutations appear in this promoter. In experiments where transcriptional activation was ...

And through the years, Gottesman has certainly built on everything she's absorbed. As an independent investigator at the National Institutes of Health (NIH)—where she set up shop in 1976—Gottesman ...

The logic that controls gene regulation in human cells Date: February 22, 2022 Source: University of Helsinki Summary: ... Only a handful of highly active transcription factors in cells.

Students will participate in a USDA-funded project to identify and characterize gene regulatory sequences throughout the genomes of 50 or more insects of agricultural and biomedical importance.

Despite extensive studies on the physiological roles of ARC neurons, it is important to emphasize that their developmental gene regulation programs are poorly understood. This highlights the ...

When the team compared mitochondrial quantity with changes in DNA methylation, a chemical modification that regulate gene activity, one gene involved in cell growth and nutrient sensing stood out. The ...