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Molecular model of a adenovirus. Image Credit: Kateryna Kon/Shutterstock.com. What are adenoviruses? Adenoviruses are non-enveloped, double-stranded DNA viruses (genome size: 34-43 kb; virion size ...
The adenovirus genome is contained within a capsid comprising 12 penton and 240 hexon subunits, plus minor structural proteins. ... Numbers represent map units.
Adenovirus genes that thwart apoptosis pathways may promote viral latency Research findings could improve usefulness of virus as effective vector for gene therapy ...
The first unbiased, genome-wide view of how spontaneous mutations are produced in DNA viruses has been generated. Jennifer Risso-Ballester, José Cuevas and Rafael Sanjuán from the Evolution and Health ...
To ensure supremely tight regulation of the adenovirus late phase, we built in a proprietary negative feedback loop, and we have demonstrated that this can repress adenovirus production by 99. ...
You especially want to take out the part of the adenovirus genome called E1; removing that makes it impossible for the virus to replicate. If you need more room for your own payload, ...
Until now the use of adenoviruses in tumor therapy has been very limited. They lack the ability to infect cancer cells and therefore cannot inject the genetic blueprints for the therapeutic molecules ...