Modern HIV medicine is based on a common genetic mutation. Now, researchers have traced where and when the mutation arose -- and how it protected our ancestors from ancient diseases.

Despite rapid advances in genome and exome sequencing, many individuals with rare diseases remain undiagnosed. In a Perspective article published in Nature Genetics, researchers at Karolinska ...

The researchers sifted through 10 billion pieces of sequencing data to build each species' 3D genome map in detail. While there was no evidence of distal regulation in the single-celled relatives ...

Immune system scientists and computational biologists are developing a new tool to investigate how the body fights disease.

By using cutting-edge long-read sequencing technology, which reads large sections of DNA without fragmentation, Sidra Medicine’s study delivers the first genome maps with unprecedented ...

Adenovirus was first detected at a median of 54 days (range −4 to +333) after BMT. Adenovirus developed in eight of 69 (11.6%) patients receiving grafts from matched unrelated or mismatched ...

Effective mucosal immunity in the intestine involves a fine balance between tolerance of the microbiome, recognition and elimination of pathogens, and inflammatory tissue injury. The anti-inflammatory ...

For scale, each human cell nucleus packs about two metres of DNA. The researchers sifted through 10 billion pieces of sequencing data to build each species’ 3D genome map in detail. While there was no ...

For scale, each human cell nucleus packs about two metres of DNA. The researchers sifted through 10 billion pieces of sequencing data to build each species’ 3D genome map in detail. While there was no ...

Viruses are known to use the genetic machinery of the human cells they invade to make copies of themselves. As part of the process, viruses leave behind remnants throughout the genetic material ...