(2020) performed genome-wide CRISPR screens in diverse mouse cancer cell ... of anti-HER2 CAR macrophages based on CD3ζ (135). A replication-deficient adenovirus vector efficiently and repeatedly ...

Modern HIV medicine is based on a common genetic mutation. Now, researchers have traced where and when the mutation arose -- and how it protected our ancestors from ancient diseases.

Despite rapid advances in genome and exome sequencing, many individuals with rare diseases remain undiagnosed. In a Perspective article published in Nature Genetics, researchers at Karolinska ...

The researchers sifted through 10 billion pieces of sequencing data to build each species' 3D genome map in detail. While there was no evidence of distal regulation in the single-celled relatives ...

A groundbreaking DNA study reveals how genetic mutations pass through generations, offering new insights into disease and ...

By using cutting-edge long-read sequencing technology, which reads large sections of DNA without fragmentation, Sidra Medicine’s study delivers the first genome maps with unprecedented ...

Plants are susceptible to a wide range of pathogens. For the common potato plant, one such threat is Pectobacterium ...

Adenovirus was first detected at a median of 54 days (range −4 to +333) after BMT. Adenovirus developed in eight of 69 (11.6%) patients receiving grafts from matched unrelated or mismatched ...

The divergence of ASIC designs makes it difficult to run commonly used modern sequencing analysis pipelines due to software ...

Effective mucosal immunity in the intestine involves a fine balance between tolerance of the microbiome, recognition and elimination of pathogens, and inflammatory tissue injury. The anti-inflammatory ...