Despite advances, the roles of genetics and microenvironment in CLL are not fully understood, and curative treatments may ...

Gene expression, where cells use the genetic information encoded in DNA to produce proteins, has been thought of as a dimmer ...

An international team of researchers led by King’s College London have identified genetic factors that may make some individuals more or less sensitive to the environments they experience.

The finding comes from one of the largest-ever analyses of gene–environment interactions for eczema. In lab models, dog allergen exposure triggered protective immune responses in skin cells with the ...

The finding comes from one of the largest-ever analyses of gene–environment interactions for eczema. In lab models, dog allergen exposure triggered protective immune responses in skin cells with ...

Panelists discuss how splice modifiers work by enhancing protein production from the SMN2 gene, with risdiplam (Evrysdi) being an oral daily medication and nusinersen (Spinraza) being administered ...

TAIJI-M relies on a gene-gene interaction network to calculate posttreatment gene expression. This approach limits its applicability to new datasets, as TAIJI-M can only predict synergy scores for ...

Our analyses determined that the emergence of PCG is largely dependent on the acquisition of unique modular gene clusters and allelic variations that confer a competitive advantage during intestinal ...

“Gene-environment interaction” (G × E) is defined as “a different effect of an environmental exposure on disease risk in subjects with different genotypes” or “a different effect of a genotype on ...

Among these are: 1) interactions between driver and modifier genes; 2) oligogenic inheritance, wherein each parent provides predisposing variants in one or multiple distinct loci; 3) interactions ...