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“The androgen receptor doesn’t follow the rules,” Dr. Wasmuth says. The different three-dimensional shapes created by these movements also allow the androgen receptor to interact with other proteins ...
Protein That Suppresses Androgen Receptors Could Improve Prostate Cancer Diagnosis, Treatment. ScienceDaily. Retrieved June 4, 2025 from www.sciencedaily.com / releases / 2009 / 05 / 090520100513.htm.
A protein that helps regulate expression of androgen receptors could prove a new focal point for staging and treating testosterone-fueled prostate cancer, Medical College of Georgia researchers say.
A protein called the androgen receptor normally functions to guide the development of the prostate—signaling the cells to stop growing, act as normal prostate cells and maintain a healthy state.
The protein SPOP, which is most frequently mutated in human prostate cancers, is a key regulator of androgen receptor activity that prevents uncontrolled growth of cells in the prostate and thus ...
The protein type of coactivators, such as p300, androgen-receptor–associated protein 70, full-steroid-receptor coactivator-1, and transcriptional intermediary factor 2, all increase the ...
Super-resolution (τ-STED) imaging of the androgen receptor in human prostate adenocarcinoma cells. The nucleus of one cell is shown, and the nuclear contour is highlighted with a white dashed line.
Protein droplets reveal new ways to inhibit transcription factors in an ... [IRB] “We had previously observed that the androgen receptor forms biomolecular condensates when even a tiny ...
Targeting the protein factories behind prostate cancer. ... When eIF4A tried to unpackage the androgen receptor mRNA in the presence of zotatifin, it got tangled up in the mRNA.
In prostate cancer, the glucocorticoid receptor can replace the activity of the androgen receptor, which is main oncogenic factor in this cancer, when its activity is inhibited by drug therapy.
A protein that helps regulate expression of androgen receptors could prove a new focal point for staging and treating testosterone-fueled prostate cancer, Medical College of Georgia researchers say.