Bleeding events occurred substantially less often with the lower dose of aspirin, reported John Burn, MD, of Newcastle ...

Inclusion criteria: Adults (18 years old or older) taking antiplatelet drugs for at least 2 weeks; scheduled for elective or emergency neurosurgery under general anaesthesia (craniotomy, spinal cord ...

Aspirin prodrugs formed by derivatization at the benzoic acid group are very difficult to obtain because the promoiety accelerates the rate of hydrolysis by plasma esterases at the neighboring acetyl ...