Despite the immense amount of genetic material present in each cell, around three billion base pairs in humans, this material needs to be accurately divided in two and allocated in equal quantities.

A new technique may force the centromere -- the mysterious stretch of DNA in the center of every chromosome -- to give up its secrets at last. The first test of the approach has yielded clues about ...

For nucleosome-encoded epigenetic information to be transmitted, an epigenetic mark requires a 'reader' for its physical recognition. CENP-N has now been identified as a reader of the ...

The chromosomal passenger complex (CPC) is involved in the proper orchestration of both mitosis and meiosis. The CPC comprises Aurora-B protein kinase, the inner centromere protein (INCENP), survivin ...