Over the past two decades, researchers have learned that DNA inside the cell nucleus naturally folds into a network of ...

A recent international research project has used advanced microscopy techniques and computational modeling to discover why ...

Researchers have used advanced microscopy and computational modeling to show how herpesvirus infection affects host-cell nucleus structure.

The organisation of the genome in three-dimensional space is a fundamental aspect of gene expression programmes that underlie cell fate and plasticity. Understanding 3D genome organisation is ...

Single-cell analyses have emerged as powerful tools for studying cellular heterogeneity and gene regulation. Single-cell chromatin accessibility ...

Chromosomes are masters of organization. These long strings of DNA fold down into an ensemble of compact structures that keep needed parts of the genome accessible while tucking away those that aren't ...

Chromosomes are masters of organization. These long strings of DNA fold down into an ensemble of compact structures that keep needed parts of the genome accessible while tucking away those that aren't ...

Colorectal cancer is one of the most prevalent tumors and a leading cause of cancer-related mortality. Despite advances achieved in recent years, resistance to available treatments remains one of the ...