CHAF1B, a histone chaperone component of the chromatin assembly factor-1 complex, is overexpressed in multiple cancers and ...

Researchers are beginning to unpick the intricate molecular choreography that ensures faithful transmission of genetic and ...

CHAF1B, a histone chaperone component of the chromatin assembly factor-1 complex, is overexpressed in multiple cancers and ...

Chromatin organization strengthens DNA for mechanically stressful processes like mitosis, helps protect DNA from damage and is important in the control of gene expression and DNA replication.

Precision gene editing is crucial for treating genetic diseases, as it enables targeted correction of specific mutations. A ...

A protein called PriC allows DNA replication to proceed in Escherichia coli when the complex that usually initiates this process is compromised.

A powerful new discovery reveals that Nup98 a protein once thought to only ferry molecules through the nucleus plays a vital ...

Can you briefly explain the concept of replication stress and its role in DNA repair? Liu: It's a really complicated topic. In really broad terms, replication stress is when the process of DNA ...

However, incomplete DNA replication or chromosome entanglement can result in the formation of DNA bridges between two daughter cells. If these bridges are not properly resolved, it can lead to ...

The mammalian liver has an extraordinary regenerative capacity, capable of fully restoring its mass and function after injury ...

Scientists at The University of Texas Health Science Center at San Antonio (UT Health San Antonio) have made one of the most ...